Watching a psychological thriller in the morning before work is like waking from a haunting, lucid dream, and trying to forget it and go about your daily life.
Side Effects starts off like a White People Problems melodrama: rich husband goes away for insider trading, wife has to start working, husband gets out and wife feels depressed, she tries a myriad of different anti-depressants, all with less than satisfactory results. One drug has completely unsatisfactory results, leading to the climactic, crazy, and meaty second half of the movie.
There's really no way to summarize the entirety of Side Effects without giving away its tricks, and even the trailer is convoluted--watch it, but know that it doesn't give you any actual information about the movie.
I'm glad I didn't know exactly what I was getting into--the twists and surprises are the linchpins of the movie, bright bursts of frenzy that briefly illuminate the drama on screen before dying away and leaving the viewer with questions that can only be answered by continuing to watch.